Whole Genome Sequencing Shows that African Swine Fever Virus Genotype IX Is Still Circulating in Domestic Pigs in All Regions of Uganda

Blood samples were collected from pigs at six abattoirs in the Kampala, Uganda metropolitan area May 2021 through June 2022, and tested for African swine fever virus. Thirty-one with cycle threshold values < 26 different geographic origins, clinical pathologic signs, Ornithodoros moubata exposure underwent whole genome sequencing. The p72 gene was used to genotype isolates, all found be IX; sequences previous IX isolates confirmed their similarity. Six of had enough coverage evaluate single nucleotide polymorphisms (SNPs). Five differed historic regional but similar SNPs one another, sixth isolate also other five even though they are IX. Whole sequencing data provide additional detail on viral evolution that can useful molecular epidemiology, understanding impact changes genes disease phenotypes, may needed vaccine targeting should a commercial become available. More virus is understand how when changing.